Platelets

Researched

Platelet Count (Thrombocytes)

Blood Cells • Last tested 2026-01-28

What It Measures

This test measures the number of platelets (thrombocytes) per microliter of blood. Platelets are the first responders to vascular injury — they aggregate at wound sites, form a plug, and release chemical signals that activate the coagulation cascade. The count reflects the balance between platelet production in bone marrow and their consumption or destruction in circulation.

Platelets are small, disc-shaped cell fragments produced by megakaryocytes in bone marrow that play a critical role in blood clotting (hemostasis) and wound healing. A platelet count is a standard component of the complete blood count (CBC) and serves as a key indicator of clotting capacity, bone marrow function, and systemic inflammation.

Current Value

239Thousand/uL
Reference Range: 150450 Thousand/uL(standard)
Optimal Range: 175300 Thousand/uL(Functional/optimal range of 175,000–300,000/µL based on functional medicine consensus and data from Cleveland Clinic and Peter Attia's longevity-focused practice. Standard lab reference range is 150,000–400,000/µL. Values at the extremes of the standard range warrant investigation. No significant male/female difference in adults, though women may have slightly higher counts.)
In Range
-20.0 (-7.7%) from previous test
150 Thousand/uLOptimal: 175300450 Thousand/uL

What High Means

Elevated platelet counts (thrombocytosis, >400,000/µL) can be reactive or primary. Reactive thrombocytosis is commonly caused by acute infection, chronic inflammation (e.g., rheumatoid arthritis, IBD), iron deficiency anemia, surgical recovery, or cancer. Primary thrombocytosis results from myeloproliferative disorders such as essential thrombocythemia or polycythemia vera. Elevated platelets increase the risk of abnormal blood clot formation (thrombosis), which can lead to stroke, pulmonary embolism, or deep vein thrombosis.

Possible Symptoms

Often asymptomatic; headaches; dizziness; chest pain; vision changes; tingling or numbness in hands/feet; easy or unusual blood clot formation; erythromelalgia (burning pain in extremities); in severe cases, stroke or heart attack symptoms.

What Low Means

Low platelet counts (thrombocytopenia, <150,000/µL) indicate either decreased production, increased destruction, or sequestration. Causes include bone marrow disorders (aplastic anemia, leukemia, myelodysplastic syndromes), autoimmune destruction (immune thrombocytopenic purpura/ITP), viral infections (HIV, hepatitis C, EBV), medications (heparin-induced thrombocytopenia, chemotherapy), liver disease with splenomegaly, and nutritional deficiencies (B12, folate). Low platelets increase bleeding risk, from easy bruising to life-threatening hemorrhage.

Possible Symptoms

Easy bruising (ecchymoses); petechiae (small red/purple spots on skin); prolonged bleeding from cuts; bleeding gums; nosebleeds; blood in urine or stool; heavy menstrual periods; fatigue; splenic enlargement symptoms; in severe cases (<20,000/µL), spontaneous internal bleeding.

Risk Factors

Thrombosis (stroke, DVT, PE) with high counts; hemorrhage and bleeding disorders with low counts; cardiovascular disease; myeloproliferative neoplasms; autoimmune disorders (ITP, lupus); liver cirrhosis; splenomegaly; disseminated intravascular coagulation (DIC); bone marrow failure syndromes; heparin-induced thrombocytopenia; gestational thrombocytopenia.

Actionable Advice

Supplements

  • Omega-3 fatty acids (EPA/DHA)
  • Vitamin B12
  • Folate
  • Iron (if deficient)
  • Vitamin K2
  • Vitamin C
  • Papaya leaf extract (for low platelets)
  • Chlorophyll/wheatgrass

Diet & Lifestyle

  • Maintain a nutrient-dense diet rich in leafy greens, lean proteins, and healthy fats
  • Address iron, B12, and folate deficiencies through diet or supplementation
  • Limit alcohol consumption — excess alcohol suppresses platelet production
  • Stay well-hydrated to support healthy blood viscosity
  • Exercise regularly but avoid extreme endurance training which can transiently lower platelets
  • Avoid unnecessary NSAID use (ibuprofen, aspirin) which impair platelet function
  • Manage chronic inflammation through anti-inflammatory diet and stress reduction
  • Get regular CBCs to monitor trends rather than single values
  • If platelets are consistently elevated, rule out iron deficiency and chronic inflammation

Ask AI

Ask questions about your Platelets results, trends, and what you can do to optimize.

Historical Trend

Reference
Optimal
Last researched Feb 14, 2026

All Readings

DateValueChange
2026-01-28239 Thousand/uL-20.0
2025-09-18259 Thousand/uL-32.0
2025-08-25291 Thousand/uL+20.0
2025-07-31271 Thousand/uL-44.0
2025-06-27315 Thousand/uL