Estradiol

Researched

Estradiol (E2)

Hormones • Last tested 2026-01-28

What It Measures

The blood concentration of estradiol, the most potent form of estrogen.

Estradiol is the primary estrogen in men, produced via aromatization of testosterone. It is essential for bone health, brain function, and cardiovascular protection — but excess can cause issues.

Current Value

103pg/mL
Reference Range: 1040 pg/mL(standard)
Optimal Range: 2030 pg/mL(Function Health, LabCorp, Quest Diagnostics)
N/A
+41.6 (+67.8%) from previous test
10 pg/mLOptimal: 203040 pg/mL

What High Means

Elevated estradiol in men (often from aromatization due to excess body fat) can cause gynecomastia, water retention, mood changes, and may suppress LH/testosterone production.

Possible Symptoms

Water retention, breast tenderness, gynecomastia, mood swings

What Low Means

Low estradiol in men increases risk of osteoporosis, joint pain, cognitive decline, and cardiovascular issues. Estrogen is protective even in men.

Possible Symptoms

Joint pain, fatigue, low libido, bone density loss

Risk Factors

Gynecomastia (high), osteoporosis (low), cardiovascular risk (low)

Actionable Advice

Supplements

  • DIM (diindolylmethane, if high)
  • Calcium D-glucarate
  • Zinc

Diet & Lifestyle

  • Reduce body fat (fat tissue aromatizes testosterone to estrogen)
  • Cruciferous vegetables support estrogen metabolism
  • Limit alcohol (increases aromatization)
  • Avoid xenoestrogens (plastics, BPA)

Ask AI

Ask questions about your Estradiol results, trends, and what you can do to optimize.

Historical Trend

Reference
Optimal
Last researched Feb 14, 2026

All Readings

DateValueChange
2026-01-28103 pg/mL+41.6
2025-09-1861.4 pg/mL-41.6
2025-08-25103 pg/mL+51.7
2025-07-3151.3 pg/mL+32.2
2025-06-2719.1 pg/mL